Satellite Symposia

Satellite Symposia are non-commercial scientific sessions supported by industry to complement the official program and to extend the educational experience of meeting attendees. They may include one or a number of speakers and may cover one or several topics, and will contain objectivity in the presentation. Satellite Symposia are not part of the official asm2014 scientific sessions as planned by the General Meeting Program Committee.

Satellite Symposia can be held Saturday, May 17 through Tuesday, May 20, outside the schedule of the official asm2014 activities.



KBase - Toward a System for Collaborative and Reproducible Inference and Modeling of Biological Function

Supported by DOE Systems Biology Knowledgebase

Westin Boston Waterfront Hotel
425 Summer Street
Meeting Room:  Harbor Ballroom III

Speakers by Topic

6:30 p.m. – 7:15 p.m.:  
Microbes analysis from genome annotation to metabolic modeling
William Riehl, Ph.D.

Software Developer, Lawrence Berkeley National Laboratory, Berkeley, CA.  
Steps to building a metabolic model reconciled with experimental growth data and predicting growth under new conditions.

7:15 p.m. – 8:00 p.m.
Microbial communities analysis and approaches to modeling  
Folker Meyer, Ph.D.

Computational Biologist, Argonne National Laboratory, Argonne, IL.
Demonstrating the analysis of a large set of community samples extracting microbial species and functions that vary between samples. Comparisons of metabolic modeling approaches will also be presented.

Program Overview

We will present two analysis pipelines that demonstrate how KBase can help researchers collaborate, and perform complex analyses.

Achieving a systems-level understanding of biology will enable researchers to predict and ultimately design how biological systems will function under certain conditions. A collaborative computational environment is needed to bring researchers together so they can share and integrate large, heterogeneous datasets and readily use this information to develop predictive models that drive scientific discovery.

We will introduce KBase (DOE Systems Biology Knowledgebase), an open-source, open-architecture framework for reproducible and collaborative computational systems biology. KBase's primary scientific aim is to integrate multiple types of functional data towards increasingly specific models of metabolic and regulatory behavior of microbes, plants and communities. We have brought together data and tools that allow probabilistic modeling of gene function, which can be used in turn to produce experimentally testable models of cellular metabolism and gene regulation.



Addressing Antimicrobial Resistant Organisms: Genetic Research and Clinical Testing

Supported by OpGen, Inc.

6:30 p.m. – 8:00 p.m.  
Westin Boston Waterfront Hotel
425 Summer Street
Meeting Room:  Stone

Speakers by Topic

Enhanced Genome Assembly and Identification of Mobile Genetic Elements Using Whole Genome Mapping
Matthew C. Riley
University of Tennessee

Multi Drug Resistant Organisms: The Threat We Face
Jennifer K. (Kristie) Johnson, Ph.D., D(ABMM)
Associate Professor, Department of Pathology, University of Maryland School of Medicine

Today’s Clinical Micro Lab: Overcoming Challenges and Still Protecting Patients
James W. Snyder, Ph.D., D(ABMM), F(AAM)
Director of Microbiology, Professor, Clinical Service, University of Louisville School of Medicine

Acuitas™ MDRO Gene Test:  Direct, Sensitive, Comprehensive
Terry Walker, Ph.D.
Vice President, R&D, OpGen, Inc.

Program Overview

The CDC reports that antibiotic resistant bacteria are one of our most serious health threats. It is a costly complex problem, sickening 2 million people and killing 23,000 each year in the US.   OpGen provides genetic services for both clinical research and comprehensive clinical testing for antimicrobial resistant organisms.  At this symposium, attendees will learn about applications of Whole Genome Mapping in clinical research and gain a deeper understanding about the clinical threat that Multi-Drug Resistant Organisms (MDROs) pose to our healthcare facilities.  Additionally, a review of one clinical laboratory’s current efforts and vision to address the threat of MDROs in the future will be presented.  Finally, OpGen will review its development and validation of the Acuitas™ MDRO Gene Test.